2′,3,4,4′,5-Pentamethoxychalcone
نویسندگان
چکیده
In the title chalcone [systemetic name 1-(2,4-dimeth-oxy-phen-yl)-3-(3,4,5-trimeth-oxy-phen-yl)prop-2-en-1-one], C(20)H(22)O(6), the dihedral angle between the plane of the two benzene rings is 7.03 (4)° with all but one of the meth-oxy groups essentially co-planar with these rings [C-C-O-C torsion angles = -76.1 (2), -0.7 (3), 1.8 (3), -6.2 (3), 2.0 (3)°]. An intra-molecular C-H⋯O inter-action occurs. The crystal packing is stabilized by weak inter-molecular C-H⋯O hydrogen bonds.
منابع مشابه
The Cytoprotective Effects of E-α-(4-Methoxyphenyl)-2',3,4,4'-Tetramethoxychalcone (E-α-p-OMe-C6H4-TMC)--A Novel and Non-Cytotoxic HO-1 Inducer.
Cell protection against different noxious stimuli like oxidative stress or chemical toxins plays a central role in the treatment of many diseases. The inducible heme oxygenase isoform, heme oxygenase-1 (HO-1), is known to protect cells against a variety of harmful conditions including apoptosis. Because a number of medium strong electrophiles from a series of α-X-substituted 2',3,4,4'-tetrameth...
متن کاملMetabolism of 2,2',3,4',5,5'-hexachlorobiphenyl (cb146) by Liver Microsomes from Rats, Hamsters and Guinea Pigs
Introduction Some hydroxy (OH)-metabolites of various PCB congeners such as 4-OH-2,2',3,4',5,5',6-heptachlorobiphenyl (CB187), 4-OH-2,2',3,4',5,5'-hexachlorobiphenyl (hexaCB) (CB146), 4-OH-2,3,3',4',5-pentachlorobiphenyl (CB107), 3'-OH-2,2',3,4,4',5'-hexaCB (CB138) and 3-OH-2,2',4,4',5,5'-hexaCB (CB153) have been found in human blood at higher concentrations. Recent studies have shown that such...
متن کاملAnti-plasmodial flavonoids from the stem bark of Erythrina abyssinica.
The ethyl acetate extract of the stem bark of Erythrina abyssinica showed anti-plasmodial activity against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum with IC(50) values of 7.9+/-1.1 and 5.3+/-0.7 microg/ml, respectively. From this extract, a new chalcone, 2',3,4,4'-tetrahydroxy-5-prenylchalcone (trivial name 5-prenylbutein) and a new flavanone...
متن کامل2′,3,4,4′-Tetramethoxychalcone
IN THE TITLE COMPOUND [SYSTEMATIC NAME: 1-(2,4-dimethoxyphenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one], C(19)H(20)O(5), the dihedral angle between the benzene rings is 26.88 (5)°. One of the meth-oxy groups is twisted slightly away from the plane [C-O-C-C torsion angle = -12.8 (3)°] while the others are almost co-planer [C-O-C-C torsion angles = -3.2 (3), 2.6 (3) and -3.6 (3)°]. The crystal pa...
متن کاملFlame retardant exposure: polybrominated diphenyl ethers in blood from Swedish workers.
Polybrominated diphenyl ethers (PBDEs) are used as additives in polymers and textiles to prohibit the development of fires. Because of the production and use of PBDEs, their lipophilic characteristics, and persistence, these compounds have become ubiquitous environmental contaminants. The aim of the present study was to determine potential exposures of PBDEs to clerks working full-time at compu...
متن کامل